Description and pharmacological properties
Green colored tablets, diamond-shaped, film-coated, engraved with “scars” on one side and “KGR 100” on the other, from 14.2 to 14.4 in length mm, width from 10.2 to 10.4 mm (for a dose of 100 mg). After taking the drug, sildenafil is rapidly absorbed. As a general rule, the main cause of impotence is inadequate blood supply to the cavernous bodies. Violation can be triggered by stress factors, nervous and physical stress, various diseases. In each of these cases, an active blood supply to the vessels is required to eliminate impotence or sexual weakness. If you buy Kamagra 100 tablets, you can do this quickly and efficiently. The medication eliminates vasospasm and smooth muscle tension. This effect is achieved due to the successful inhibition of phosphodiesterase. In the presence of stimulatory stimulation, the penis fills with blood and reaches a rapidly erect state. Sexual intercourse takes place in standard mode, ending with ejaculation. In the future, if desired, a man may continue to have sex, after which he will hold a respite for a few minutes. Sildenafil is 96% bound to plasma proteins. Protein binding is independent of the total concentration of sildenafil. Sildenafil is metabolized in the liver. The main circulating metabolite undergoes further metabolism. According to the selectivity of the effect, the metabolite is comparable to sildenafil and its in vitro activity is approx. 50% of the activity of sildenafil itself.
In many cases, it helps to tackle erectile dysfunction, but not always and not at all. Sildenafil citrate helps to dilate blood vessels, increase blood flow to the penis, and achieve an erection in response to sexual stimulation. But it should be remembered that the substance itself may not cause erection if there is no natural attraction for the couple. Kamagra can be taken without regard to food intake, but its effect may be slower if you only ate well and then took a pill. This medication should be taken approximately one hour before sexual intercourse. You should not combine the intake of Kamagra with grapefruit or grapefruit juice, as this may interfere with the normal effect of the medicine. It is recommended not to take more than 1 50 mg tablet per day. Day. If you haven’t had an erection for a long time, you can have several attempts to achieve it, even with Kamagra. Drinking large amounts of alcohol can also make an erection difficult.
How should this medicine be used?
In case of erectile dysfunction characterized by inability to obtain or maintain an erection of the penis sufficient for a satisfactory sexual relation. Kamagra is effective only in the presence of sexual stimulation. Despite the high effectiveness of sildenafil, a certain number of patients remain with those whose use of this drug does not lead to an improvement in erection. In many cases, this is due to an incorrect drug. Patients, especially at the beginning of treatment, should be advised to take sildenafil on an empty stomach at least 30 minutes before sexual activity begins. It is also important to make it clear to patients that the effect of the drug develops only on the basis of appropriate sexual arousal and is largely dependent on it. In many cases, treatment should start with 100 mg, providing the maximum response at the start of the treatment and inspiring patients with confidence in the treatment. Moreover, studies have shown that in some patients the maximum effect of sildenafil is achieved between 6 and 8 doses, and therefore, in many patients, a final evaluation of the efficacy of the drug should be made after several attempts to use it. .
Side effects from taking Kamagra are generally rare and short-lived. Very often men experience dizziness, headaches, and redness. It is worth noting that this drug has undergone several clinical trials. In the implementation process, it was found that the intensity of the manifestation and the duration of the side effects largely depend on the dose of the drug and on the individual characteristics of the body for a particular patient, like:
– spatial disorientation (dizziness), tinnitus
– tachycardia, palpitations
– arterial hypertension, arterial hypotension
– nosebleeds, sinuses
– upper abdominal pain, gastroesophageal reflux disease, vomiting, dry mouth
– hyperemia, hot flashes
– color distortion of vision, visual disturbance, blurred vision
– acute stroke, transient ischemic attack, seizures *, relapse of a seizure *, fainting
– nasal congestion
– dyspepsia, nausea
– oral hyperesthesia
– sudden cardiac death, heart attack
– feeling of tightness in the throat, swelling of the nose, dryness of the nasal mucosa
– bleeding from the penis, increased erection irritability
In addition, the following negative phenomena can be observed in patients who are extremely rare: a feeling of heat (such as an increase in body temperature), local pain, increased irritability, fatigue and general weakness, swelling of the face, chills, pain in the the chest. It is important to report suspected adverse reactions identified after registration of the drug. This allows you to continue monitoring the relationship between the benefits and risks of the medication.